Uterotonic effect of rectal misoprostol as preoperative medication for assessment of intraoperative and postoperative blood loss in cesarean delivery

Background: Postpartum hemorrhage is the leading cause of maternal mortality and it's prevention has been identified as key component safe motherhood. Misoprostol an effective uterotonic for prophylaxis control PPH. Aim our study was to evaluate effect preoperative rectal misoprostol (400μg) on blood loss during after cesarean delivery.Methods: It a randomised controlled trial done 200 women scheduled elective delivery. Eligible participants were randomized into two groups. In group 100 received 400 μg per tablet just spinal anaesthesia while assigned did not receive tablet.Results: The mean intra operative postoperative lower in than 345.98±79.57 ml 114±19.97 versus 408.6±63.68 136.38±24.81 ml, respectively. difference between hematocrit values also significantly (33.43±1.93 33.64±1.82)Conclusions: it concluded that reducing intraoperative loss, thus preventing postpartum incidence overall morbidity mortality.